≡

Nuclear Transcription Factor Y Beta (NFYb)

[Edit]

CBF-A; CBF-B; HAP3; NF-YB; CAAT box DNA-binding protein subunit B; Nuclear transcription factor Y subunit B

Nuclear Transcription Factor Y Beta (NFYb)
CCC F666
HGNC 7805
MGI 97317
PubMed 23389444
RGD 3172
UniProt P25208
Wiki NFYB
Nuclear transcription factor Y subunit beta is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes.
This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.Li et al. (1991) assigned the NFYB gene to human chromosome 12 by in situ hybridization.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Transcription Factor Y Beta (NFYb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Transcription Factor Y Beta (NFYb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Transcription Factor Y Beta (NFYb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Transcription Factor Y Beta (NFYb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Transcription Factor Y Beta (NFYb) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Transcription Factor Y Beta (NFYb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Transcription Factor Y Beta (NFYb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Transcription Factor Y Beta (NFYb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Transcription Factor Y Beta (NFYb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Transcription Factor Y Beta (NFYb) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Transcription Factor Y Beta (NFYb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Transcription Factor Y Beta (NFYb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Transcription Factor Y Beta (NFYb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Transcription Factor Y Beta (NFYb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Transcription Factor Y Beta (NFYb) ELISA Kit Customized Service Offer
  1. "Intron-exon organization of the NF-Y genes. Tissue-specific splicing modifies an activation domain."J. Biol. Chem. 267:8984-8990(1992) [PubMed] [Europe PMC] [Abstract]
  2. "Evolutionary variation of the CCAAT-binding transcription factor NF-Y."Nucleic Acids Res. 20:1087-1091(1992) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro."Nucleic Acids Res. 32:3632-3641(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y."J. Biol. Chem. 278:1336-1345(2003) [PubMed] [Europe PMC] [Abstract]
  8. "Sequence-specific transcription factor NF-Y displays histone-like DNA binding and H2B-like ubiquitination."Cell 152:132-143(2013) [PubMed] [Europe PMC] [Abstract]