Microfibrillar Associated Protein 3 (MFAP3)

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Microfibrillar Associated Protein 3 (MFAP3)
Microfibrils of diameter 10-12 nm are found either in association with elastin or independently and are an important component of the extracellular matrix of many tissues. The proteins composing the microfibrils are distinct from elastin. The largest and possibly the most important of these are the fibrillins, 350-kD glycoproteins that form integral parts of the microfibril structure; see fibrillin-1 (FBN1). Another component of microfibrils is microfibrillar-associated protein-2 (MFAP2). Other proteins localized to the elastic fiber microfibrils include the enzyme lysyl oxidase (LOX) and microfibrillar-associated protein-1 (MFAP1). Abrams et al. (1995) cloned and characterized microfibrillar-associated protein-3 (MFAP3). Monospecific antibodies prepared against the recombinant expressed protein reacted with the microfibrils found in ocular zonules.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF588Hu01 Recombinant Microfibrillar Associated Protein 3 (MFAP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF588Hu01 Polyclonal Antibody to Microfibrillar Associated Protein 3 (MFAP3) WB; IHC; ICC; IP.
Assay Kits SEF588Hu ELISA Kit for Microfibrillar Associated Protein 3 (MFAP3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Microfibrillar Associated Protein 3 (MFAP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Microfibrillar Associated Protein 3 (MFAP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Microfibrillar Associated Protein 3 (MFAP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Microfibrillar Associated Protein 3 (MFAP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Microfibrillar Associated Protein 3 (MFAP3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Microfibrillar Associated Protein 3 (MFAP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Microfibrillar Associated Protein 3 (MFAP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Microfibrillar Associated Protein 3 (MFAP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Microfibrillar Associated Protein 3 (MFAP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Microfibrillar Associated Protein 3 (MFAP3) ELISA Kit Customized Service Offer
  1. "Molecular cloning of the microfibrillar protein MFAP3 and assignment of the gene to human chromosome 5q32-q33.2."Genomics 26:47-54(1995) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Diagnostic exome sequencing in persons with severe intellectual disability."N. Engl. J. Med. 367:1921-1929(2012) [PubMed] [Europe PMC] [Abstract]