Lysyl Oxidase Like Protein 4 (LOXL4)
[Edit]LOXC; Lysyl oxidase homolog 4; Lysyl oxidase-related protein C
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Lysyl oxidase homolog 4 is a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin.
A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPF554Hu01 | Recombinant Lysyl Oxidase Like Protein 4 (LOXL4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPF554Hu02 | Recombinant Lysyl Oxidase Like Protein 4 (LOXL4) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAF554Hu01 | Polyclonal Antibody to Lysyl Oxidase Like Protein 4 (LOXL4) | WB; IHC; ICC; IP. |
| PAF554Hu02 | Polyclonal Antibody to Lysyl Oxidase Like Protein 4 (LOXL4) | WB; IHC; ICC; IP. | |
| LAF554Hu71 | Biotin-Linked Polyclonal Antibody to Lysyl Oxidase Like Protein 4 (LOXL4) | WB; IHC; ICC. | |
| Assay Kits | SEF554Hu | ELISA Kit for Lysyl Oxidase Like Protein 4 (LOXL4) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPF554Mu01 | Recombinant Lysyl Oxidase Like Protein 4 (LOXL4) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Lysyl Oxidase Like Protein 4 (LOXL4) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Lysyl Oxidase Like Protein 4 (LOXL4) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Lysyl Oxidase Like Protein 4 (LOXL4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Lysyl Oxidase Like Protein 4 (LOXL4) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Lysyl Oxidase Like Protein 4 (LOXL4) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Lysyl Oxidase Like Protein 4 (LOXL4) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Lysyl Oxidase Like Protein 4 (LOXL4) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Lysyl Oxidase Like Protein 4 (LOXL4) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Lysyl Oxidase Like Protein 4 (LOXL4) | ELISA Kit Customized Service Offer |
- "Molecular cloning and biological activity of a novel lysyl oxidase-related gene expressed in cartilage."J. Biol. Chem. 276:24023-24029(2001) [PubMed] [Europe PMC] [Abstract]
- "Cloning and characterization of a fifth human lysyl oxidase isoenzyme: the third member of the lysyl oxidase-related subfamily with four scavenger receptor cysteine-rich domains."Matrix Biol. 20:493-496(2001) [PubMed] [Europe PMC] [Abstract]
- "A novel human lysyl oxidase-like gene (LOXL4) on chromosome 10q24 has an altered scavenger receptor cysteine rich domain."Matrix Biol. 20:487-491(2001) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]