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Kinesin Family, Member C3 (KIFC3)

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Kinesin-like protein KIFC3

Kinesin Family, Member C3 (KIFC3)
CCC F530
HGNC 6326
MGI 109202
PubMed 11581287
RGD 1307693
UniProt Q9BVG8
Wiki KIFC3
KIFC3 belongs to the large superfamily of kinesins, molecular motors that use the energy of ATP hydrolysis to translocate cargoes along microtubules.
KIFC3 is a minus end-directed microtubule motor protein, therefore it accumulates in regions where minus ends of microtubules assemble. In polarized epithelial cells, KIFC3 is localized on membrane organelles immediately beneath the apical plasma membrane of renal tubular epithelial cells in vivo and polarized MDCK II cells in vitro. Flotation assay, coupled with detergent extraction, demonstrated that KIFC3 is associated with Triton X-100-insoluble membrane organelles, and that it overlaps with apically transported TGN-derived vesicles.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member C3 (KIFC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member C3 (KIFC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member C3 (KIFC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member C3 (KIFC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member C3 (KIFC3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member C3 (KIFC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member C3 (KIFC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member C3 (KIFC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member C3 (KIFC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member C3 (KIFC3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member C3 (KIFC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member C3 (KIFC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member C3 (KIFC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member C3 (KIFC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member C3 (KIFC3) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The sequence and analysis of duplication-rich human chromosome 16." Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Cloning of a novel C-terminal kinesin (KIFC3) that maps to human chromosome 16q13-q21 and thus is a candidate gene for Bardet-Biedl syndrome."Genomics 52:219-222(1998) [PubMed] [Europe PMC] [Abstract]
  5. "Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts."Cell 135:948-959(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Crystal structure of the KIFC3 motor domain in complex with ADP."Submitted (JUN-2006) to the PDB data bank