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Kinesin Family, Member 13B (KIF13B)

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GAKIN; Kinesin-like protein GAKIN

Kinesin Family, Member 13B (KIF13B)
CCC F514
HGNC 14405
MGI 1098265
PubMed 20194617
RGD 1303307
UniProt Q9NQT8
KIF13B contains a consensus ATP/GTP-binding motif within its N-terminal motor domain; a stalk domain containing several short alpha-helical segments; and a CAP-gly motif in its C terminus characteristic of microtubule-based cytoskeleton components. KIF13B has several putative serine/threonine phosphorylation sites and a putative tyrosine phosphorylation site. The N-terminal motor domain of KIF13B shares 98% identity with the motor domain of mouse Kif13b. Northern blot analysis revealed a single 8.5-kb transcript in all tissues tested, with highest abundance in kidney, pancreas, brain, and testis. Western blot analysis of Jurkat T cells revealed an apparent molecular mass of 250 kD, and immunolocalization revealed a punctate, cytoplasmic distribution in resting T cells.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member 13B (KIF13B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member 13B (KIF13B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member 13B (KIF13B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member 13B (KIF13B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member 13B (KIF13B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member 13B (KIF13B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member 13B (KIF13B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member 13B (KIF13B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member 13B (KIF13B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member 13B (KIF13B) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member 13B (KIF13B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member 13B (KIF13B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member 13B (KIF13B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member 13B (KIF13B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member 13B (KIF13B) ELISA Kit Customized Service Offer
  1. "GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes."J. Biol. Chem. 275:28774-28784(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."DNA Res. 5:169-176(1998) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  9. "Par1b/MARK2 phosphorylates kinesin-like motor protein GAKIN/KIF13B to regulate axon formation."Mol. Cell. Biol. 30:2206-2219(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  13. "Solution structure of the CAP-Gly domain in human kinesin-like protein KIF13B."Submitted (NOV-2005) to the PDB data bank