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Kinesin Family, Member 13A (KIF13A)

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Kinesin-like protein RBKIN

Kinesin Family, Member 13A (KIF13A)
CCC F513
HGNC 14566
MGI 1098264
PubMed 11106728
RGD 1307825
UniProt Q9H1H9
Wiki KIF13A
Kif13a, a plus end-directed microtubule-dependent motor protein that associates with beta-1 adaptin (AP1B1), a subunit of the AP1 adaptor complex.
The 1,749-amino acid mouse Kif13a protein contains an N-terminal motor domain and an AF6/cno domain. The authors found that the cargo vesicles of Kif13a contain AP1 and mannose 6-phosphate receptor (M6PR). Overexpression of Kif13a resulted in mislocalization of AP1 and M6PR, and functional blockade of Kif13a reduced cell-surface expression of M6PR. Thus, the authors concluded that KIF13A transports M6PR-containing vesicles and targets M6PR from the trans-Golgi network to the plasma membrane via direct interaction with the AP1 adaptor complex.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member 13A (KIF13A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member 13A (KIF13A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member 13A (KIF13A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member 13A (KIF13A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member 13A (KIF13A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member 13A (KIF13A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member 13A (KIF13A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member 13A (KIF13A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member 13A (KIF13A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member 13A (KIF13A) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Kinesin Family, Member 13A (KIF13A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Kinesin Family, Member 13A (KIF13A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Kinesin Family, Member 13A (KIF13A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Kinesin Family, Member 13A (KIF13A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Kinesin Family, Member 13A (KIF13A) ELISA Kit Customized Service Offer
  1. "Identification of the human KIF13A gene homologous to Drosophila kinesin-73 and candidate for schizophrenia."Genomics 74:36-44(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Genomic amplification in retinoblastoma narrowed to 0.6 megabase on chromosome 6p containing a kinesin-like gene, RBKIN."Cancer Res. 62:967-971(2002) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "AP-1 and KIF13A coordinate endosomal sorting and positioning during melanosome biogenesis."J. Cell Biol. 187:247-264(2009) [PubMed] [Europe PMC] [Abstract]
  8. "PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody."Nat. Cell Biol. 12:362-371(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]