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Carboxypeptidase D (CPD)

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gp180; Metallocarboxypeptidase D

Carboxypeptidase D (CPD)
CCC F321
HGNC 2301
MGI 107265
PubMed 17641957
RGD 2393
UniProt O75976
Wiki CPD
The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene.The predicted 1,377-amino acid protein contains a signal sequence, 3 tandem carboxypeptidase homology domains, and a C-terminal putative transmembrane domain. The 3 carboxypeptidase domains have sequence similarity to the regulatory B-type carboxypeptidase family. Overall, the amino acid sequences of CPD and gp180 are 75% identical. Northern blot analysis revealed CPD expression as multiple mRNAs in pancreas, placenta, heart, and skeletal muscle.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Carboxypeptidase D (CPD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Carboxypeptidase D (CPD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Carboxypeptidase D (CPD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Carboxypeptidase D (CPD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Carboxypeptidase D (CPD) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Carboxypeptidase D (CPD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Carboxypeptidase D (CPD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Carboxypeptidase D (CPD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Carboxypeptidase D (CPD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Carboxypeptidase D (CPD) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Carboxypeptidase D (CPD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Carboxypeptidase D (CPD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Carboxypeptidase D (CPD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Carboxypeptidase D (CPD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Carboxypeptidase D (CPD) ELISA Kit Customized Service Offer
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  2. "Sequence of human carboxypeptidase D reveals it to be a member of the regulatory carboxypeptidase family with three tandem active site domains."Biochem. J. 327:81-87(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
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  10. "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  14. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]