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Centrin 1 (CETN1)

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CEN1; CETN; Centrin,EF-Hand Protein 1; Caltractin isoform 2

Centrin 1 (CETN1)
CCC F281
HGNC 1866
MGI 1347086
PubMed 24284873
RGD 620246
UniProt Q12798
Wiki CETN1
Centrin-1 is a protein plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle.
The predicted 172-amino acid protein contains 4 putative EF-hand calcium-binding domains. Sequence analysis revealed that CETN1 is highly conserved; it shares 81% and 68% protein sequence identity with Xenopus centrin and Chlamydomonas centrin, respectively. CETN1 isolated from HeLa cell extracts has a molecular mass of approximately 20 kD and a pI of 4.5 to 4.7.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF281Hu01 Recombinant Centrin 1 (CETN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF281Hu01 Polyclonal Antibody to Centrin 1 (CETN1) WB; IHC; ICC; IP.
Assay Kits SEF281Hu ELISA Kit for Centrin 1 (CETN1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF281Mu01 Recombinant Centrin 1 (CETN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Centrin 1 (CETN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centrin 1 (CETN1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centrin 1 (CETN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centrin 1 (CETN1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Centrin 1 (CETN1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Centrin 1 (CETN1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Centrin 1 (CETN1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Centrin 1 (CETN1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Centrin 1 (CETN1) ELISA Kit Customized Service Offer
  1. "Cloning of a cDNA encoding human centrin, an EF-hand protein of centrosomes and mitotic spindle poles."J. Cell Sci. 107:9-16(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Pitchfork regulates primary cilia disassembly and left-right asymmetry."Dev. Cell 19:66-77(2010) [PubMed] [Europe PMC] [Abstract]