Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1)
[Edit]CACNA2; CACNL2A; CCHL2A; MHS3
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CACNa2d1 encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Calcium Channel, Voltage Dependent, Alpha 2/Delta Subunit 1 (CACNa2d1) | ELISA Kit Customized Service Offer |
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- "Identification of a disulfide bridge essential for structure and function of the voltage-gated Ca(2+) channel alpha(2)delta-1 auxiliary subunit."Cell Calcium 51:22-30(2012) [PubMed] [Europe PMC] [Abstract]