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Serine/Arginine Rich Splicing Factor 9 (SRSF9)

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SRp30c; SFRS9; Pre-mRNA-splicing factor SRp30C; Splicing factor, arginine/serine-rich 9

Serine/Arginine Rich Splicing Factor 9 (SRSF9)
CCC F109
HGNC 10791
MGI 104896
PubMed 22178073
RGD 1309495
UniProt Q13242
Recombinant SRp30c produced in E. coli restored splicing to a cytosolic HeLa S100 extract deficient in SR factors, suggesting that SRp30c protein is involved in mRNA formation.Proximal spinal muscular atrophy (SMA) is caused by the homozygous loss of SMN1. SMN2, a nearly identical copy gene, is present in all SMA patients; however, this gene cannot provide protection from disease due to the aberrant splicing of a critical exon. SMN2-derived transcripts predominantly lack SMN exon 7 due to a single nonpolymorphic nucleotide difference (C in SMN1 vs T in SMN2). SRp30c did not directly associate with SMN exon 7; rather, its association with the exonic enhancer was mediated by a direct interaction with TRA2-beta. In the absence of the TRA2-beta binding site, SRp30c failed to associate with SMN exon 7.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serine/Arginine Rich Splicing Factor 9 (SRSF9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serine/Arginine Rich Splicing Factor 9 (SRSF9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serine/Arginine Rich Splicing Factor 9 (SRSF9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serine/Arginine Rich Splicing Factor 9 (SRSF9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serine/Arginine Rich Splicing Factor 9 (SRSF9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serine/Arginine Rich Splicing Factor 9 (SRSF9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serine/Arginine Rich Splicing Factor 9 (SRSF9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serine/Arginine Rich Splicing Factor 9 (SRSF9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serine/Arginine Rich Splicing Factor 9 (SRSF9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serine/Arginine Rich Splicing Factor 9 (SRSF9) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serine/Arginine Rich Splicing Factor 9 (SRSF9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serine/Arginine Rich Splicing Factor 9 (SRSF9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serine/Arginine Rich Splicing Factor 9 (SRSF9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serine/Arginine Rich Splicing Factor 9 (SRSF9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serine/Arginine Rich Splicing Factor 9 (SRSF9) ELISA Kit Customized Service Offer
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