G Protein Alpha 11 (GNa11)

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GA11; Guanine Nucleotide-Binding Protein Subunit Alpha-11; Guanine nucleotide-binding protein G(y) subunit alpha

G Protein Alpha 11 (GNa11)
Gna11 is upstream of Gna15, and the region separating the 2 genes is 6 kb long. Phylogenetic trees revealed an approximately 6-fold higher rate of change in Gna15 than in Gna11. Mouse Gna11 and Gna15 are tandemly duplicated in a head-to-tail array. Gna11, is ubiquitously expressed, whereas expression of the downstream gene, Gna15, is restricted to hematopoietic cells. There was no evidence for alternative splicing within the coding sequence of either gene. G-alpha-q (GNAQ) and G-alpha-11 were required for maintenance of basal blood pressure and for development of salt-induced hypertension. In contrast, lack of G-alpha-12 (GNA12) and G-alpha-13 (GNA13) and their effector, Larg (ARHGEF12), did not alter normal blood pressure regulation, but blocked development of salt-induced hypertension.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF061Hu01 Recombinant G Protein Alpha 11 (GNa11) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAF061Hu21 Monoclonal Antibody to G Protein Alpha 11 (GNa11) WB; IHC; ICC; IP.
PAF061Hu01 Polyclonal Antibody to G Protein Alpha 11 (GNa11) WB,IHC,ICC/IF; FCM
Assay Kits SEF061Hu ELISA Kit for G Protein Alpha 11 (GNa11) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G Protein Alpha 11 (GNa11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G Protein Alpha 11 (GNa11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G Protein Alpha 11 (GNa11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G Protein Alpha 11 (GNa11) CLIA Kit Customized Service Offer
n/a ELISA Kit for G Protein Alpha 11 (GNa11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant G Protein Alpha 11 (GNa11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to G Protein Alpha 11 (GNa11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to G Protein Alpha 11 (GNa11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for G Protein Alpha 11 (GNa11) CLIA Kit Customized Service Offer
n/a ELISA Kit for G Protein Alpha 11 (GNa11) ELISA Kit Customized Service Offer
  1. "Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells."Proc. Natl. Acad. Sci. U.S.A. 88:3907-3911(1991) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]