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Ribosomal Protein L7 (RPL7)

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Ribosomal Protein L7 (RPL7)
CCC F047
HGNC 10363
MGI 98073
PubMed 8360149
RGD 735169
UniProt P18124
Wiki RPL7
RPL7 encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribosomal Protein L7 (RPL7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribosomal Protein L7 (RPL7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribosomal Protein L7 (RPL7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribosomal Protein L7 (RPL7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribosomal Protein L7 (RPL7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribosomal Protein L7 (RPL7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribosomal Protein L7 (RPL7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribosomal Protein L7 (RPL7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribosomal Protein L7 (RPL7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribosomal Protein L7 (RPL7) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ribosomal Protein L7 (RPL7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ribosomal Protein L7 (RPL7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ribosomal Protein L7 (RPL7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ribosomal Protein L7 (RPL7) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ribosomal Protein L7 (RPL7) ELISA Kit Customized Service Offer
  1. "Structural and functional properties of ribosomal protein L7 from humans and rodents."Nucleic Acids Res. 21:223-231(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Identification of a transcript that is down-regulated in senescent human fibroblasts. Cloning, sequence analysis, and regulation of the human L7 ribosomal protein gene."J. Biol. Chem. 268:18474-18480(1993) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
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  5. , Submitted (JUL-2007) to UniProtKB
  6. "Human ribosomal protein L7 inhibits cell-free translation in reticulocyte lysates and affects the expression of nuclear proteins upon stable transfection into Jurkat T-lymphoma cells."Nucleic Acids Res. 23:195-202(1995) [PubMed] [Europe PMC] [Abstract]
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  8. "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  12. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  13. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  14. "Structures of the human and Drosophila 80S ribosome."Nature 497:80-85(2013) [PubMed] [Europe PMC] [Abstract]