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Nuclear RNA Export Factor 3 (NXF3)

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TAPL3; TAP-like protein 3

Nuclear RNA Export Factor 3 (NXF3)
CCC E923
HGNC 8073
MGI 2685230
PubMed 24520286
RGD 1564923
UniProt Q9H4D5
NXF3 is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE923Hu01 Recombinant Nuclear RNA Export Factor 3 (NXF3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Nuclear RNA Export Factor 3 (NXF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear RNA Export Factor 3 (NXF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear RNA Export Factor 3 (NXF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear RNA Export Factor 3 (NXF3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear RNA Export Factor 3 (NXF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear RNA Export Factor 3 (NXF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear RNA Export Factor 3 (NXF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear RNA Export Factor 3 (NXF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear RNA Export Factor 3 (NXF3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear RNA Export Factor 3 (NXF3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear RNA Export Factor 3 (NXF3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear RNA Export Factor 3 (NXF3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear RNA Export Factor 3 (NXF3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear RNA Export Factor 3 (NXF3) ELISA Kit Customized Service Offer
  1. "TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture."Mol. Cell. Biol. 20:8996-9008(2000) [PubMed] [Europe PMC] [Abstract]
  2. "Two closely related human nuclear export factors utilize entirely distinct export pathways."Mol. Cell 8:397-406(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation."Curr. Biol. 11:1381-1391(2001) [PubMed] [Europe PMC] [Abstract]