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Catenin Delta 2 (CTNNd2)

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NPRAP; GT24; Neurojungin; Cadherin Associated Protein Delta 2; Neural Plakophilin-Related Arm-Repeat Protein

Catenin Delta 2 (CTNNd2)
CCC E902
HGNC 2516
MGI 1195966
PubMed 21106062
RGD 620734
UniProt Q9UQB3
Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids long. These proteins can be divided into subfamilies based on the number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Delta-1-catenin and Delta-2-catenin are members of a subfamily of proteins with ten Armadillo-repeats.
Catenin,Delta 2 is expressed in the brain where it is important for normal cognitive development. Like beta-catenin and gamma-catenin, delta-catenins seem to interact with presenilins. These catenin-presenilin interaction have implications for cadherin function and regulation of cell-to-cell adhesion.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Catenin Delta 2 (CTNNd2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Catenin Delta 2 (CTNNd2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Catenin Delta 2 (CTNNd2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Catenin Delta 2 (CTNNd2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Catenin Delta 2 (CTNNd2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Catenin Delta 2 (CTNNd2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Catenin Delta 2 (CTNNd2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Catenin Delta 2 (CTNNd2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Catenin Delta 2 (CTNNd2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Catenin Delta 2 (CTNNd2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Catenin Delta 2 (CTNNd2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Catenin Delta 2 (CTNNd2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Catenin Delta 2 (CTNNd2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Catenin Delta 2 (CTNNd2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Catenin Delta 2 (CTNNd2) ELISA Kit Customized Service Offer
  1. "Presenilin 1 interaction in the brain with a novel member of the Armadillo family."NeuroReport 8:2085-2090(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Delta-catenin, an adhesive junction-associated protein which promotes cell scattering."J. Cell Biol. 144:519-532(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Isolation of human delta-catenin and its binding specificity with presenilin 1."NeuroReport 10:563-568(1999) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin."J. Neurochem. 72:999-1008(1999) [PubMed] [Europe PMC] [Abstract]
  6. "Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family."Differentiation 61:293-304(1997) [PubMed] [Europe PMC] [Abstract]
  7. "Isolation of cDNAs from the Cri-du-chat critical region by direct screening of a chromosome 5-specific cDNA library."Genome Res. 7:118-127(1997) [PubMed] [Europe PMC] [Abstract]
  8. "cdk5 modulates beta- and delta-catenin/Pin1 interactions in neuronal cells."J. Cell. Biochem. 100:738-749(2007) [PubMed] [Europe PMC] [Abstract]
  9. "Delta-catenin-induced dendritic morphogenesis. An essential role of p190RhoGEF interaction through Akt1-mediated phosphorylation."J. Biol. Chem. 283:977-987(2008) [PubMed] [Europe PMC] [Abstract]
  10. "PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells."J. Cell Sci. 122:3374-3384(2009) [PubMed] [Europe PMC] [Abstract]
  11. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]