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Catenin Alpha 2 (CTNNa2)

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CAPR; CAP-R; Cadherin-Associated Protein,Related; Alpha-catenin-related protein; Alpha N-catenin

Catenin Alpha 2 (CTNNa2)
CCC E899
HGNC 2510
MGI 88275
PubMed 22833195
RGD 1305060
UniProt P26232
Cell-cell and cell-matrix adhesions involve transmembrane glycoproteins such as cell adhesion molecules and integrins, which are thought to function via interactions of their cytoplasmic domains with proteins associated with the cytoskeleton. Vinculin and talin are examples.Despite the homology, the protein was probably not the actual human homolog of alpha-catenin because of atypical mouse/human mutation rates computed from the 2 sequences and because of the finding of a partial cDNA sequence 89% identical to CAP102 within a human expressed sequence tag (EST) library.
CAPR also differed from CAP102 by the presence of a 48-residue insert, suggesting the situation previously described for the metavinculin/vinculin system.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Catenin Alpha 2 (CTNNa2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Catenin Alpha 2 (CTNNa2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Catenin Alpha 2 (CTNNa2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Catenin Alpha 2 (CTNNa2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Catenin Alpha 2 (CTNNa2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Catenin Alpha 2 (CTNNa2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Catenin Alpha 2 (CTNNa2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Catenin Alpha 2 (CTNNa2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Catenin Alpha 2 (CTNNa2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Catenin Alpha 2 (CTNNa2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Catenin Alpha 2 (CTNNa2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Catenin Alpha 2 (CTNNa2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Catenin Alpha 2 (CTNNa2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Catenin Alpha 2 (CTNNa2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Catenin Alpha 2 (CTNNa2) ELISA Kit Customized Service Offer
  1. "Characterization and chromosomal assignment of a human cDNA encoding a protein related to the murine 102-kDa cadherin-associated protein (alpha-catenin)."Genomics 15:13-20(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Nuclear translocation of alphaN-catenin by the novel zinc finger transcriptional repressor ZASC1."Exp. Cell Res. 311:1-13(2005) [PubMed] [Europe PMC] [Abstract]
  7. "Regulation of a novel alphaN-catenin splice variant in schizophrenic smokers."Am. J. Med. Genet. B Neuropsychiatr. Genet. 147:759-768(2008) [PubMed] [Europe PMC] [Abstract]
  8. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]