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A Kinase Anchor Protein 10 (AKAP10)

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D-AKAP2; PRKA10; Dual-Specificity A-Kinase Anchoring Protein 2; Protein Kinase A Anchoring Protein 10; Mitochondrial A Kinase PPKA Anchor Protein 10

A Kinase Anchor Protein 10 (AKAP10)
CCC E890
HGNC 368
MGI 1890218
PubMed 17485678
RGD 1308869
UniProt O43572
Wiki AKAP10
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell.
AKAP10 encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant A Kinase Anchor Protein 10 (AKAP10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to A Kinase Anchor Protein 10 (AKAP10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to A Kinase Anchor Protein 10 (AKAP10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for A Kinase Anchor Protein 10 (AKAP10) CLIA Kit Customized Service Offer
n/a ELISA Kit for A Kinase Anchor Protein 10 (AKAP10) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant A Kinase Anchor Protein 10 (AKAP10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to A Kinase Anchor Protein 10 (AKAP10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to A Kinase Anchor Protein 10 (AKAP10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for A Kinase Anchor Protein 10 (AKAP10) CLIA Kit Customized Service Offer
n/a ELISA Kit for A Kinase Anchor Protein 10 (AKAP10) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant A Kinase Anchor Protein 10 (AKAP10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to A Kinase Anchor Protein 10 (AKAP10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to A Kinase Anchor Protein 10 (AKAP10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for A Kinase Anchor Protein 10 (AKAP10) CLIA Kit Customized Service Offer
n/a ELISA Kit for A Kinase Anchor Protein 10 (AKAP10) ELISA Kit Customized Service Offer
  1. "Cloning and mitochondrial localization of full-length D-AKAP2, a protein kinase A anchoring protein."Proc. Natl. Acad. Sci. U.S.A. 98:3220-3225(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  5. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  6. "Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate AKAP10 in heart rhythm regulation."Proc. Natl. Acad. Sci. U.S.A. 104:8461-8466(2007) [PubMed] [Europe PMC] [Abstract]