Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3)
[Edit]GLUR-K3; GLUR3; GLURC; gluR-C; AMPA-selective glutamate receptor 3
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists.
Glutamate receptor 3 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternative splicing at this locus results in several different isoforms which may vary in their signal transduction properties.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE803Hu01 | Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAE803Hu01 | Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | WB; ICC; IHC-P; IHC-F; ELISA. |
MAE803Hu21 | Monoclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | WB; IHC; ICC; IP. | |
Assay Kits | SEE803Hu | ELISA Kit for Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE803Mu01 | Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPE803Mu02 | Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAE803Mu01 | Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | WB; IHC; ICC; IP. |
PAE803Mu02 | Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | WB; IHC; ICC; IP. | |
Assay Kits | SEE803Mu | ELISA Kit for Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3) | ELISA Kit Customized Service Offer |
- "Human glutamate receptor hGluR3 flip and flop isoforms: cloning and sequencing of the cDNAs and primary structure of the proteins."Biochim. Biophys. Acta 1219:563-566(1994) [PubMed] [Europe PMC] [Abstract]
- "Characterization of the human glutamate receptor subunit 3 gene (GRIA3), a candidate for bipolar disorder and nonspecific X-linked mental retardation."Genomics 62:356-368(1999) [PubMed] [Europe PMC] [Abstract]
- "Candidate gene analysis in Rett syndrome and the identification of 21 SNPs in Xq."Am. J. Med. Genet. 90:69-71(2000) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence of the human X chromosome." Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
- "Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins."Neuron 68:1082-1096(2010) [PubMed] [Europe PMC] [Abstract]
- "Mutations in ionotropic AMPA receptor 3 alter channel properties and are associated with moderate cognitive impairment in humans." Proc. Natl. Acad. Sci. U.S.A. 104:18163-18168(2007) [PubMed] [Europe PMC] [Abstract]