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Netrin G2 (NtnG2)

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Lmnt2; Laminet-2

Netrin G2 (NtnG2)
CCC E704
HGNC 14288
MGI 2159341
PubMed 17507910
RGD 1307089
UniProt Q96CW9
Wiki NTNG2
NETRIN-G2 associated with the development of nervous system is disclosed. Its whole cDNA length is 2428 bp and it is positioned at chromosome 9q34. The coded protein has 530 amino acids (about 60 KD). It may be used for the medicine to treat the diseases in nervous system.
Netrin-G1 and netrin-G2, belonging to a vertebrate-specific subfamily of the netrin family, distribute on axons of distinct neuronal pathways.Netrin G2 encodes a GPI-linked membrane protein which is a member of the netrin/UNC6 family. Netrin G2 promotes neurite outgrowth of both axons and dendrites. There are 2 isofroms produced by alternative splicing. The protein possesses a number of potential N-glycosylation sites.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE704Hu01 Recombinant Netrin G2 (NtnG2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Netrin G2 (NtnG2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Netrin G2 (NtnG2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Netrin G2 (NtnG2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Netrin G2 (NtnG2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Netrin G2 (NtnG2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Netrin G2 (NtnG2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Netrin G2 (NtnG2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Netrin G2 (NtnG2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Netrin G2 (NtnG2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Netrin G2 (NtnG2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Netrin G2 (NtnG2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Netrin G2 (NtnG2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Netrin G2 (NtnG2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Netrin G2 (NtnG2) ELISA Kit Customized Service Offer
  1. "Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 8:85-95(2001) [PubMed] [Europe PMC] [Abstract].
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  3. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  4. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract].
  6. "Structural basis for cell surface patterning through NetrinG-NGL interactions."EMBO J. 30:4479-4488(2011) [PubMed] [Europe PMC] [Abstract]
  7. "Crystal structure of the ligand binding domain of netrin G2."J. Mol. Biol. 414:723-734(2011) [PubMed] [Europe PMC] [Abstract]