Minichromosome Maintenance Deficient 3 (MCM3)
[Edit]HCC5; P1-MCM3; P1.h; RLFB; RLF subunit beta; DNA replication licensing factor MCM3; DNA polymerase alpha holoenzyme-associated protein P1
MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins.
This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE653Hu01 | Recombinant Minichromosome Maintenance Deficient 3 (MCM3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAE653Hu01 | Polyclonal Antibody to Minichromosome Maintenance Deficient 3 (MCM3) | WB; IHC; ICC; IP. |
Assay Kits | SEE653Hu | ELISA Kit for Minichromosome Maintenance Deficient 3 (MCM3) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE653Mu01 | Recombinant Minichromosome Maintenance Deficient 3 (MCM3) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAE653Mu01 | Polyclonal Antibody to Minichromosome Maintenance Deficient 3 (MCM3) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Minichromosome Maintenance Deficient 3 (MCM3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Minichromosome Maintenance Deficient 3 (MCM3) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Minichromosome Maintenance Deficient 3 (MCM3) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Minichromosome Maintenance Deficient 3 (MCM3) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Minichromosome Maintenance Deficient 3 (MCM3) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Minichromosome Maintenance Deficient 3 (MCM3) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Minichromosome Maintenance Deficient 3 (MCM3) | ELISA Kit Customized Service Offer |
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- , Submitted (JUL-2007) to UniProtKB
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