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Cyclin Dependent Kinase 11B (CDK11B)

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CDC2L1; CDK11; PITSLREA; PK58; Cell division cycle 2-like kinase 1; PITSLRE serine/threonine-protein kinase CDC2L1; Galactosyltransferase-associated protein kinase p58/GTA

Cyclin Dependent Kinase 11B (CDK11B)
CCC E617
HGNC 1729
MGI 88353
PubMed 1774066
UniProt P21127
Wiki CDC2L1
CDK11B encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE617Hu01 Recombinant Cyclin Dependent Kinase 11B (CDK11B) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Cyclin Dependent Kinase 11B (CDK11B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cyclin Dependent Kinase 11B (CDK11B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cyclin Dependent Kinase 11B (CDK11B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cyclin Dependent Kinase 11B (CDK11B) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cyclin Dependent Kinase 11B (CDK11B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cyclin Dependent Kinase 11B (CDK11B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cyclin Dependent Kinase 11B (CDK11B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cyclin Dependent Kinase 11B (CDK11B) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cyclin Dependent Kinase 11B (CDK11B) ELISA Kit Customized Service Offer
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  20. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  21. "Patterns of somatic mutation in human cancer genomes." Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]