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TATA Box Binding Protein Associated Factor 7 (TAF7)

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TAF2F; TAFII55; Transcription Initiation Factor TFIID Subunit 7; RNA polymerase II TBP-associated factor subunit F; Transcription initiation factor TFIID 55 kDa subunit

TATA Box Binding Protein Associated Factor 7 (TAF7)
CCC E557
HGNC 11541
MGI 1346348
PubMed 22711989
UniProt Q15545
Wiki TAF7
TAF7 is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators.
The protein is required for transcription by promoters targeted by RNA polymerase II.The predicted protein is 349 amino acids (40 kD) and contains 40% charged residues, which may account for its larger than expected electrophoretic mobility. The mRNA was expressed in all tissues examined. The authors showed that TAFII55 interacts with TAFII230, the largest subunit of TFIID, and with multiple transcription activators, including Sp1, YY1, USF, CTF, and adenoviral E1A.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TATA Box Binding Protein Associated Factor 7 (TAF7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TATA Box Binding Protein Associated Factor 7 (TAF7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TATA Box Binding Protein Associated Factor 7 (TAF7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TATA Box Binding Protein Associated Factor 7 (TAF7) CLIA Kit Customized Service Offer
n/a ELISA Kit for TATA Box Binding Protein Associated Factor 7 (TAF7) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TATA Box Binding Protein Associated Factor 7 (TAF7) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TATA Box Binding Protein Associated Factor 7 (TAF7) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TATA Box Binding Protein Associated Factor 7 (TAF7) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TATA Box Binding Protein Associated Factor 7 (TAF7) CLIA Kit Customized Service Offer
n/a ELISA Kit for TATA Box Binding Protein Associated Factor 7 (TAF7) ELISA Kit Customized Service Offer
  1. "Multiple interactions between hTAFII55 and other TFIID subunits. Requirements for the formation of stable ternary complexes between hTAFII55 and the TATA-binding protein."J. Biol. Chem. 271:19774-19780(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning of an intrinsic human TFIID subunit that interacts with multiple transcriptional activators."Science 267:531-536(1995) [PubMed] [Europe PMC] [Abstract]
  3. "The intronless and TATA-less human TAFII55 gene contains a functional initiator and a downstream promoter element."J. Biol. Chem. 276:25503-25511(2001) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF."Cell 121:873-885(2005) [PubMed] [Europe PMC] [Abstract]
  7. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Structural basis for the methylation site specificity of SET7/9."Nat. Struct. Mol. Biol. 13:140-146(2006) [PubMed] [Europe PMC] [Abstract]
  9. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  10. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  13. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  14. "Phosphorylation-dependent regulation of cyclin D1 and cyclin A gene transcription by TFIID subunits TAF1 and TAF7."Mol. Cell. Biol. 32:3358-3369(2012) [PubMed] [Europe PMC] [Abstract]
  15. "Transcriptional coactivator CIITA, a functional homolog of TAF1, has kinase activity."Biochim. Biophys. Acta 1829:1184-1190(2013) [PubMed] [Europe PMC] [Abstract]
  16. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]