Immunoglobulin Superfamily, Member 11 (IGSF11)
[Edit]BTIGSF; CXADRL1; Igsf13; VSIG3; Brain and testis-specific immunoglobulin superfamily protein; V-set and immunoglobulin domain-containing protein 3
![Immunoglobulin Superfamily, Member 11 (IGSF11)](/upload/item/img/Immunoglobulin-Superfamily--Member-11-(IGSF11)-94549.jpg)
IGSF11 is an immunoglobulin (Ig) superfamily member that is preferentially expressed in brain and testis. It shares significant homology with coxsackievirus and adenovirus receptor (CXADR) and endothelial cell-selective adhesion molecule (ESAM).The predicted 431-amino acid type I transmembrane protein is 88% identical to the mouse protein and shares homology with the IGSF members CXADR and ESAM.
IGSF11 has a 23-residue signal peptide, 3 potential extracellular N-linked glycosylation sites, an extracellular V-type Ig-like domain, an extracellular C2-type Ig-like domain, and a 170-residue cytoplasmic tail with a C-terminal PDZ-interacting motif. Each of the Ig-like domains contains 2 cysteines.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Immunoglobulin Superfamily, Member 11 (IGSF11) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Immunoglobulin Superfamily, Member 11 (IGSF11) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Immunoglobulin Superfamily, Member 11 (IGSF11) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Immunoglobulin Superfamily, Member 11 (IGSF11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Immunoglobulin Superfamily, Member 11 (IGSF11) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Immunoglobulin Superfamily, Member 11 (IGSF11) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Immunoglobulin Superfamily, Member 11 (IGSF11) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Immunoglobulin Superfamily, Member 11 (IGSF11) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Immunoglobulin Superfamily, Member 11 (IGSF11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Immunoglobulin Superfamily, Member 11 (IGSF11) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Immunoglobulin Superfamily, Member 11 (IGSF11) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Immunoglobulin Superfamily, Member 11 (IGSF11) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Immunoglobulin Superfamily, Member 11 (IGSF11) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Immunoglobulin Superfamily, Member 11 (IGSF11) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Immunoglobulin Superfamily, Member 11 (IGSF11) | ELISA Kit Customized Service Offer |
- "Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas."Cancer Sci. 96:498-506(2005) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
- "IGSF11 gene, frequently up-regulated in intestinal-type gastric cancer, encodes adhesion molecule homologous to CXADR, FLJ22415 and ESAM."Int. J. Oncol. 23:525-531(2003) [PubMed] [Europe PMC] [Abstract]
- "BT-IgSF, a novel immunoglobulin superfamily protein, functions as a cell adhesion molecule."J. Cell. Physiol. 204:919-926(2005) [PubMed] [Europe PMC] [Abstract]