Ovarian Cancer Overexpressed Protein 1 (OVCOV1)

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SLC35C2; CGI-15; Solute Carrier Family 35 Member C2

Ovarian Cancer Overexpressed Protein 1 (OVCOV1)
Oxygenation levels play an important role in the regulation of cellular invasiveness which occurs during early implantation when the trophoblast cells invade the uterus as well as during tumour progression and metastasis. SLC35C2, which is regulated by oxygen tension, is induced in hypoxic trophoblast cells and is overexpressed in ovarian cancer. Two protein isoforms are encoded by transcript variants of this gene.Ubiquitously expressed although the level of expression is tissue dependent. Overexpressed in ovarian cancer.
The SLC gene nomenclature system was originally proposed by the Human Genome Organization (HUGO) and is the basis for the official HUGO names of the genes that encode these transporters.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ovarian Cancer Overexpressed Protein 1 (OVCOV1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ovarian Cancer Overexpressed Protein 1 (OVCOV1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ovarian Cancer Overexpressed Protein 1 (OVCOV1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ovarian Cancer Overexpressed Protein 1 (OVCOV1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ovarian Cancer Overexpressed Protein 1 (OVCOV1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ovarian Cancer Overexpressed Protein 1 (OVCOV1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ovarian Cancer Overexpressed Protein 1 (OVCOV1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ovarian Cancer Overexpressed Protein 1 (OVCOV1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ovarian Cancer Overexpressed Protein 1 (OVCOV1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ovarian Cancer Overexpressed Protein 1 (OVCOV1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ovarian Cancer Overexpressed Protein 1 (OVCOV1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ovarian Cancer Overexpressed Protein 1 (OVCOV1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ovarian Cancer Overexpressed Protein 1 (OVCOV1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ovarian Cancer Overexpressed Protein 1 (OVCOV1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ovarian Cancer Overexpressed Protein 1 (OVCOV1) ELISA Kit Customized Service Offer
  1. "Assignment of OVCOV1 (alias CGI-15) to human chromosome 20 band q13.1-->q13.2 by fluorescent in situ hybridization."Cytogenet. Cell Genet. 94:252-253(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics."Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Identification, molecular characterization, and tissue expression of OVCOV1."Mamm. Genome 13:619-624(2002) [PubMed] [Europe PMC] [Abstract]
  7. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Slc35c2 promotes Notch1 fucosylation and is required for optimal Notch signaling in mammalian cells."J. Biol. Chem. 285:36245-36254(2010) [PubMed] [Europe PMC] [Abstract]
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  12. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]