ZRT And IRT Related Protein 3 (ZIP3)

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SLC39A3; Solute Carrier Family 39 Member 3; Zrt- and Irt-like protein 3; Zinc transporter ZIP3

ZRT And IRT Related Protein 3 (ZIP3)
ZIP1 (SLC39A1), ZIP2 (SLC39A2), and ZIP3 (SLC39A3). The 3 deduced human proteins share greater than 49% similarity.By immunohistochemistry analysis of human normal and malignant prostate tissue sections, they determined that, like SLC39A1, both SLC39A2 and SLC39A3 are downregulated in malignant cells in situ along with the depletion of zinc levels. SLC39A2 and SLC39A3 were localized predominantly at the apical cell membrane, which is in contrast to the SLC39A1 localization at the basolateral membrane.
SLC39A1 is important for the extraction of zinc from circulation as the primary source of cellular zinc, whereas SLC39A2 and SLC39A3 are important for retention of the zinc in the cellular compartment.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ZRT And IRT Related Protein 3 (ZIP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ZRT And IRT Related Protein 3 (ZIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ZRT And IRT Related Protein 3 (ZIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ZRT And IRT Related Protein 3 (ZIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for ZRT And IRT Related Protein 3 (ZIP3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ZRT And IRT Related Protein 3 (ZIP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ZRT And IRT Related Protein 3 (ZIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ZRT And IRT Related Protein 3 (ZIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ZRT And IRT Related Protein 3 (ZIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for ZRT And IRT Related Protein 3 (ZIP3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ZRT And IRT Related Protein 3 (ZIP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ZRT And IRT Related Protein 3 (ZIP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ZRT And IRT Related Protein 3 (ZIP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ZRT And IRT Related Protein 3 (ZIP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for ZRT And IRT Related Protein 3 (ZIP3) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  4. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]