Cationic Amino Acid Transporter 1 (CAT1)

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SLC7A1; HCAT1; ATRC1; ERR; Solute Carrier Family 7 Member 1,Cationic Amino Acid Transporter,y+; Ecotropic Retroviral Receptor; High Affinity Cationic Amino Acid Transporter 1

Cationic Amino Acid Transporter 1 (CAT1)
Susceptibility to murine ecotropic retroviruses is attributed to the binding of the virus envelope to the membrane receptor encoded by the Rec1 gene. HCAT1 was identified as the principal transporter of the cationic amino acids, arginine, lysine, and ornithine in mouse cells. the Rec1 gene mapped to mouse chromosome 5 by analysis of murine-hamster somatic cell hybrids. Using a human cDNA obtained by homology to Rec1, Albritton et al. (1992) determined the location of the human cationic amino acid transporter by somatic cell genetics, in situ hybridization, and RFLP linkage analysis. The studies indicated that ATRC1 is located at 13q12-q14, closely linked to ATP1AL1. The CEPH consortium linkage map of chromosome 13 published by Bowcock et al. (1993) showed ATRC1 to be distal to ATP1AL1.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cationic Amino Acid Transporter 1 (CAT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cationic Amino Acid Transporter 1 (CAT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cationic Amino Acid Transporter 1 (CAT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cationic Amino Acid Transporter 1 (CAT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cationic Amino Acid Transporter 1 (CAT1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE401Mu01 Recombinant Cationic Amino Acid Transporter 1 (CAT1) Positive Control; Immunogen; SDS-PAGE; WB.
RPE401Mu02 Recombinant Cationic Amino Acid Transporter 1 (CAT1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE401Mu01 Polyclonal Antibody to Cationic Amino Acid Transporter 1 (CAT1) WB; IHC; ICC; IP.
PAE401Mu02 Polyclonal Antibody to Cationic Amino Acid Transporter 1 (CAT1) WB; IHC; ICC; IP.
Assay Kits SEE401Mu ELISA Kit for Cationic Amino Acid Transporter 1 (CAT1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cationic Amino Acid Transporter 1 (CAT1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cationic Amino Acid Transporter 1 (CAT1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cationic Amino Acid Transporter 1 (CAT1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cationic Amino Acid Transporter 1 (CAT1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cationic Amino Acid Transporter 1 (CAT1) ELISA Kit Customized Service Offer
  1. "Molecular cloning and characterization of a novel human gene homologous to the murine ecotropic retroviral receptor."Virology 185:10-17(1991) [PubMed] [Europe PMC] [Abstract]
  2. "The human cationic amino acid transporter (ATRC1): physical and genetic mapping to 13q12-q14."Genomics 12:430-434(1992) [PubMed] [Europe PMC] [Abstract]
  3. "Identification of three cationic amino acid transporters in placental trophoblast: cloning, expression, and characterization of hCAT-1."J. Membr. Biol. 171:55-62(1999) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]