Potassium Chloride Cotransporters 1 (KCC1)
[Edit]SLC12A4; hKCC1; Solute Carrier Family 12 Member 4,Potassium/Chloride Transporters; Chloride Potassium Symporter 4; Electroneutral potassium-chloride cotransporter 1
![Potassium Chloride Cotransporters 1 (KCC1)](/upload/item/img/Potassium-Chloride-Cotransporters-1-(KCC1)-94376.jpg)
The full-length sequence was obtained from EST clones and by RT-PCR of HEK293 cell RNA. The 1,085-amino acid KCC1 protein is 24 to 25% identical to NKCC1 and SLC12A3 and shares 97% identity with rabbit KCC1. The overall structure of KCC1 is similar to that of other cation-chloride cotransporters, with 12 predicted transmembrane regions, a large extracellular loop with potential N-linked glycosylation sites, and cytoplasmic N- and C-terminal domains. Northern blot analysis revealed that KCC1 is expressed ubiquitously. KCC1 exhibits the functional properties of the red cell K-Cl cotransporter, including stimulation by swelling and N-ethylmaleimide, and low affinities for rubidium, chloride, and bumetanide.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPE376Hu01 | Recombinant Potassium Chloride Cotransporters 1 (KCC1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | n/a | Monoclonal Antibody to Potassium Chloride Cotransporters 1 (KCC1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Potassium Chloride Cotransporters 1 (KCC1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Potassium Chloride Cotransporters 1 (KCC1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Potassium Chloride Cotransporters 1 (KCC1) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Potassium Chloride Cotransporters 1 (KCC1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Potassium Chloride Cotransporters 1 (KCC1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Potassium Chloride Cotransporters 1 (KCC1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Potassium Chloride Cotransporters 1 (KCC1) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Potassium Chloride Cotransporters 1 (KCC1) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Potassium Chloride Cotransporters 1 (KCC1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Potassium Chloride Cotransporters 1 (KCC1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Potassium Chloride Cotransporters 1 (KCC1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEE376Ra | ELISA Kit for Potassium Chloride Cotransporters 1 (KCC1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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