≡

Plakophilin 4 (PKP4)

[Edit]

Plakophilin 4 (PKP4)
CCC E341
HGNC 9026
MGI 109281
PubMed 12615965
RGD 1307840
UniProt Q99569
Wiki PKP4
Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120(ctn)/plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF. PKP4 may be a component of desmosomal plaque and other adhesion plaques and is thought to be involved in regulating junctional plaque organization and cadherin function. Multiple transcript variants have been found for this gene, but the full-length nature of only two of them have been described so far.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Plakophilin 4 (PKP4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Plakophilin 4 (PKP4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Plakophilin 4 (PKP4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Plakophilin 4 (PKP4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Plakophilin 4 (PKP4) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Plakophilin 4 (PKP4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Plakophilin 4 (PKP4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Plakophilin 4 (PKP4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Plakophilin 4 (PKP4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Plakophilin 4 (PKP4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Plakophilin 4 (PKP4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Plakophilin 4 (PKP4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Plakophilin 4 (PKP4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Plakophilin 4 (PKP4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Plakophilin 4 (PKP4) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of a new armadillo family member, p0071, associated with the junctional plaque: evidence for a subfamily of closely related proteins."J. Cell Sci. 109:2767-2778(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."Anal. Chem. 76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  6. "The armadillo protein p0071 regulates Rho signalling during cytokinesis."Nat. Cell Biol. 8:1432-1440(2006) [PubMed] [Europe PMC] [Abstract]
  7. "Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry."Proteomics 7:868-874(2007) [PubMed] [Europe PMC] [Abstract]
  8. "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
  9. "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."Mol. Cell 31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
  10. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  11. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  12. "PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells."J. Cell Sci. 122:3374-3384(2009) [PubMed] [Europe PMC] [Abstract]
  13. "Large-scale proteomics analysis of the human kinome."Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
  14. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  15. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  16. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  17. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  18. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]