Lactate Dehydrogenase C (LDHC)
[Edit]LDH-C; CT32; LDHX; LDH3; Cancer/Testis Antigen 32; LDH testis subunit
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Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region.
Lactate dehydrogenases exist in four distinct enzyme classes. Two of them are cytochrome c-dependent enzymes with each acting on either D-lactate (EC 1.1.2.4) or L-lactate (EC 1.1.2.3). The other two are NAD(P)-dependent enzymes with each acting on either D-lactate (EC 1.1.1.28) or L-lactate (EC 1.1.1.27). This article is about the NAD(P)-dependent L-lactate dehydrogenase.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE131Hu01 | Recombinant Lactate Dehydrogenase C (LDHC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAE131Hu01 | Polyclonal Antibody to Lactate Dehydrogenase C (LDHC) | WB; IHC; ICC; IP. |
| MAE131Hu21 | Monoclonal Antibody to Lactate Dehydrogenase C (LDHC) | WB; IHC; ICC; IP. | |
| Assay Kits | SEE131Hu | ELISA Kit for Lactate Dehydrogenase C (LDHC) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Lactate Dehydrogenase C (LDHC) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Lactate Dehydrogenase C (LDHC) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Lactate Dehydrogenase C (LDHC) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Lactate Dehydrogenase C (LDHC) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Lactate Dehydrogenase C (LDHC) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPE131Ra01 | Recombinant Lactate Dehydrogenase C (LDHC) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APE131Ra01 | Active Lactate Dehydrogenase C (LDHC) | Cell culture; Activity Assays. | |
| Antibodies | PAE131Ra01 | Polyclonal Antibody to Lactate Dehydrogenase C (LDHC) | WB; IHC; ICC; IP. |
| MAE131Ra21 | Monoclonal Antibody to Lactate Dehydrogenase C (LDHC) | WB; IHC; ICC; IP. | |
| Assay Kits | SEE131Ra | ELISA Kit for Lactate Dehydrogenase C (LDHC) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Epitopes of human testis-specific lactate dehydrogenase deduced from a cDNA sequence."Proc. Natl. Acad. Sci. U.S.A. 84:5311-5315(1987) [PubMed] [Europe PMC] [Abstract]
- "Human testicular lactate dehydrogenase-C gene is interrupted by six introns at positions homologous to those of LDH-A (muscle) and LDH-B (heart) genes."Biochem. Biophys. Res. Commun. 159:579-583(1989) [PubMed] [Europe PMC] [Abstract]
- "Human testicular lactate dehydrogenase-C gene: cDNA sequence and putative alternative splicing at the 5' noncoding region."J. Genet. Mol. Biol. 1:72-76(1990)
- "A spermatogenesis-related gene expression profile in human spermatozoa and its potential clinical applications."J. Mol. Med. 82:317-324(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]