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Ephrin B3 (EFNB3)

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EFL6; EPLG8; LERK8; EPH-related receptor transmembrane ligand ELK-L3; EPH-related receptor tyrosine kinase ligand 8

Ephrin B3 (EFNB3)
CCC E113
HGNC 3228
MGI 109196
PubMed 11107140
RGD 2541
UniProt Q15768
Wiki EFNB3
EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function.
The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ephrin B3 (EFNB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ephrin B3 (EFNB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ephrin B3 (EFNB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ephrin B3 (EFNB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ephrin B3 (EFNB3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ephrin B3 (EFNB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ephrin B3 (EFNB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ephrin B3 (EFNB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ephrin B3 (EFNB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ephrin B3 (EFNB3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ephrin B3 (EFNB3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ephrin B3 (EFNB3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ephrin B3 (EFNB3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ephrin B3 (EFNB3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ephrin B3 (EFNB3) ELISA Kit Customized Service Offer
  1. "cDNA cloning, chromosomal localization, and expression pattern of EPLG8, a new member of the EPLG gene family encoding ligands of EPH-related protein-tyrosine kinase receptors."Genomics 41:17-24(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Elk-L3, a novel transmembrane ligand for the Eph family of receptor tyrosine kinases, expressed in embryonic floor plate, roof plate and hindbrain segments."Oncogene 13:1343-1352(1996) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Signal peptide prediction based on analysis of experimentally verified cleavage sites."Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
  6. "EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains."Neuron 22:511-524(1999) [PubMed] [Europe PMC] [Abstract]
  7. "Two key residues in ephrinB3 are critical for its use as an alternative receptor for Nipah virus."PLoS Pathog. 2:78-86(2006) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]