Protocadherin Beta 11 (PCDHb11)

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Cadherin ME2

Protocadherin Beta 11 (PCDHb11)
PCDHb11 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protocadherin Beta 11 (PCDHb11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protocadherin Beta 11 (PCDHb11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protocadherin Beta 11 (PCDHb11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protocadherin Beta 11 (PCDHb11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protocadherin Beta 11 (PCDHb11) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protocadherin Beta 11 (PCDHb11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protocadherin Beta 11 (PCDHb11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protocadherin Beta 11 (PCDHb11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protocadherin Beta 11 (PCDHb11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protocadherin Beta 11 (PCDHb11) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protocadherin Beta 11 (PCDHb11) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protocadherin Beta 11 (PCDHb11) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protocadherin Beta 11 (PCDHb11) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protocadherin Beta 11 (PCDHb11) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protocadherin Beta 11 (PCDHb11) ELISA Kit Customized Service Offer
  1. "A striking organization of a large family of human neural cadherin-like cell adhesion genes."Cell 97:779-790(1999) [PubMed] [Europe PMC] [Abstract]
  2. "The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number."FEBS Lett. 495:120-125(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]