Protocadherin Beta 12 (PCDHb12)
PCDHb12 is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected.Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protocadherin Beta 12 (PCDHb12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protocadherin Beta 12 (PCDHb12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protocadherin Beta 12 (PCDHb12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protocadherin Beta 12 (PCDHb12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protocadherin Beta 12 (PCDHb12) ELISA Kit Customized Service Offer
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