Protocadherin Gamma C3 (PCDHgC3)

[Edit]

PC43; PCDH2; PC-43; Cadherin-Like 2; Protocadherin 2; Protocadherin 43

Protocadherin Gamma C3 (PCDHgC3)
PCDHGC3 is 1 of 22 tandemly arranged genes within the PCDHG gene cluster on chromosome 5q31. The 22 PCDHG genes function as 'variable' exons that are individually spliced to a downstream constant region to form distinct PCDHG transcripts. The variable PCDHG exons encode the extracellular and transmembrane domains of the protocadherin protein, and the common region encodes the intracellular domain. Like pc42, human pc43 contains an N-terminal extracellular domain, a transmembrane domain, and a C-terminal cytoplasmic region. On Western blots of extracts of a human neuroblastoma cell line, pc43 migrated at 150 kD. Immunofluorescence microscopy localized pc43 to the periphery of cells, primarily in cell-cell contact sites. Cells expressing pc43 showed cell aggregation activity.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protocadherin Gamma C3 (PCDHgC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protocadherin Gamma C3 (PCDHgC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protocadherin Gamma C3 (PCDHgC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protocadherin Gamma C3 (PCDHgC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protocadherin Gamma C3 (PCDHgC3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protocadherin Gamma C3 (PCDHgC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protocadherin Gamma C3 (PCDHgC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protocadherin Gamma C3 (PCDHgC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protocadherin Gamma C3 (PCDHgC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protocadherin Gamma C3 (PCDHgC3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protocadherin Gamma C3 (PCDHgC3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protocadherin Gamma C3 (PCDHgC3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protocadherin Gamma C3 (PCDHgC3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protocadherin Gamma C3 (PCDHgC3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protocadherin Gamma C3 (PCDHgC3) ELISA Kit Customized Service Offer
  1. "Protocadherins: a large family of cadherin-related molecules in central nervous system."EMBO J. 12:2249-2256(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Nonsyndromic deafness DFNA1 associated with mutation of a human homolog of the Drosophila gene diaphanous."Science 278:1315-1318(1997) [PubMed] [Europe PMC] [Abstract]
  3. "A striking organization of a large family of human neural cadherin-like cell adhesion genes."Cell 97:779-790(1999) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]