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Perilipin 5 (PLIN5)

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LSDP5; LSDA5; OXPAT; PAT-1; MLDP; Lipid Storage Droplet Protein 5

Perilipin 5 (PLIN5)
CCC E039
HGNC 33196
MGI 1914218
PubMed 22127648
UniProt Q00G26
Members of the perilipin family, such as PLIN5, coat intracellular lipid storage droplets and protect them from lipolytic degradation.
By searching EST databases using a conserved perilipin motif, Dalen et al. (2007) identified human PLIN5, which they called LSDP5. The predicted 463-amino acid protein is 74% identical to the mouse protein. Northern blot analysis of human tissues revealed expression of a major 2.5-kb transcript in skeletal muscle and liver, with weaker expression in heart and kidney. In heart, a 5.0-kb transcript was also expressed. Fluorescence microscopy demonstrated expression of mouse Lsdp5 around lipid storage droplets in transfected cells. Lsdp5 expression was upregulated by fasting independently of Ppara.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE039Hu01 Recombinant Perilipin 5 (PLIN5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAE039Hu01 Polyclonal Antibody to Perilipin 5 (PLIN5) WB; IHC; ICC; IP.
MAE039Hu21 Monoclonal Antibody to Perilipin 5 (PLIN5) WB; IHC; ICC; IP.
Assay Kits SEE039Hu ELISA Kit for Perilipin 5 (PLIN5) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Perilipin 5 (PLIN5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Perilipin 5 (PLIN5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Perilipin 5 (PLIN5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Perilipin 5 (PLIN5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Perilipin 5 (PLIN5) ELISA Kit Customized Service Offer
  1. "LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues."Biochim. Biophys. Acta 1771:210-227(2007) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5."J. Physiol. (Lond.) 591:657-675(2013) [PubMed] [Europe PMC] [Abstract]
  6. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]