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Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb)

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PP-1B; PPP1CD; Serine/threonine-protein phosphatase PP1-beta catalytic subunit

Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb)
CCC E027
HGNC 9282
MGI 104871
PubMed 23382248
RGD 3376
UniProt P62140
Wiki PPP1CB
Protein phosphatase-1 (PP1) is 1 of 4 major serine/threonine-specific protein phosphatases involved in the dephosphorylation of a variety of proteins. These enzymes work in opposition to the protein kinases to control the level of phosphorylation. PP1 has 3 catalytic subunits, designated alpha, beta, and gamma. PP1-beta is also referred to as PP1-delta. PPP1Cb is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE027Hu01 Recombinant Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Phosphatase 1, Catalytic Subunit Beta Isoform (PPP1Cb) ELISA Kit Customized Service Offer
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  16. "GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis."Nature 459:455-459(2009) [PubMed] [Europe PMC] [Abstract]
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  19. "SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1."Sci. Signal. 3:RA32-RA32(2010) [PubMed] [Europe PMC] [Abstract]
  20. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  21. "Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock."PLoS ONE 6:E21325-E21325(2011) [PubMed] [Europe PMC] [Abstract]
  22. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  23. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  24. "Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-alpha in rheumatoid arthritis."Nat. Med. 19:322-328(2013) [PubMed] [Europe PMC] [Abstract]