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Cyclic AMP Response Element Binding Protein 5 (CREB5)

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CRE-BPA; cAMP-responsive element-binding protein 5

Cyclic AMP Response Element Binding Protein 5 (CREB5)
CCC D998
HGNC 16844
MGI 2443973
PubMed 21132541
UniProt Q02930
Wiki CREB5
CREB is a protein that is a transcription factor. It binds to certain DNA sequences called cAMP response elements (CRE) and, thereby, increases or decreases the transcription of the downstream genes. CREB was first described in 1987 as a cAMP-responsive transcription factor regulating the somatostatin gene.
Cyclic AMP-responsive element-binding protein 5 is a protein belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD998Hu01 Recombinant Cyclic AMP Response Element Binding Protein 5 (CREB5) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD998Hu01 Polyclonal Antibody to Cyclic AMP Response Element Binding Protein 5 (CREB5) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Cyclic AMP Response Element Binding Protein 5 (CREB5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cyclic AMP Response Element Binding Protein 5 (CREB5) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cyclic AMP Response Element Binding Protein 5 (CREB5) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cyclic AMP Response Element Binding Protein 5 (CREB5) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cyclic AMP Response Element Binding Protein 5 (CREB5) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cyclic AMP Response Element Binding Protein 5 (CREB5) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cyclic AMP Response Element Binding Protein 5 (CREB5) ELISA Kit Customized Service Offer
  1. "Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1."J. Biol. Chem. 268:4259-4266(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Regulation of trans-activating capacity of CRE-BPa by phorbol ester tumor promoter TPA."Oncogene 8:2749-2758(1993) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Human protein factory for converting the transcriptome into an in vitro-expressed proteome." Nat. Methods 5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
  5. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]