Taxilin Beta (TXLNb)

[Edit]

MDP77; C6orf198; Chromosome 6 Open Reading Frame 198; Muscle-derived protein 77

Taxilin Beta (TXLNb)
By searching databases for sequences similar to the long coiled-coil region of alpha-taxilin, followed by PCR of a brain cDNA library, Nogami et al. (2004) cloned TXLNB. The deduced 684-amino acid protein has a calculated molecular mass of 76.5 kD. The long coiled-coil region of TXLNB spans amino acids 140 to 456. Western blot analysis of rat tissues detected abundant expression in skeletal muscle and heart.
Using C-terminally truncated syntaxins for in vitro protein pull-down assays, Nogami et al. (2004) demonstrated that epitope-tagged human TXLNB and native rat Txlnb bound to syntaxin 1A (STX1A) and, to a lesser extent, to STX4A (186591), but not to STX3A, STX7, or STX8 . Binding of TXLNB to truncated STX1A and STX4A was dose-dependent and saturable.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD825Hu01 Recombinant Taxilin Beta (TXLNb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD825Hu01 Polyclonal Antibody to Taxilin Beta (TXLNb) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Taxilin Beta (TXLNb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Taxilin Beta (TXLNb) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Taxilin Beta (TXLNb) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Taxilin Beta (TXLNb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Taxilin Beta (TXLNb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Taxilin Beta (TXLNb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Taxilin Beta (TXLNb) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD825Ra01 Recombinant Taxilin Beta (TXLNb) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Taxilin Beta (TXLNb) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Taxilin Beta (TXLNb) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Taxilin Beta (TXLNb) CLIA Kit Customized Service Offer
n/a ELISA Kit for Taxilin Beta (TXLNb) ELISA Kit Customized Service Offer
  1. "Muscle-specific protein MDP77 specifically promotes motor nerve regeneration in rats."Neurosci. Lett. 360:175-177(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Identification and characterization of taxilin isoforms."Biochem. Biophys. Res. Commun. 319:936-943(2004) [PubMed] [Europe PMC] [Abstract]