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Low Density Lipoprotein Receptor Related Protein 12 (LRP12)

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ST7; Suppressor of tumorigenicity 7 protein

Low Density Lipoprotein Receptor Related Protein 12 (LRP12)
CCC D745
HGNC 31708
MGI 2443132
PubMed 23408821
RGD 1304943
UniProt Q9Y561
Low Density Lipoprotein Receptor Related Protein 12 is a member of the low-density lipoprotein receptor related protein family.
The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants.Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.
Widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas, but not in tissues consisting of a large number of epithelial cells, such as liver and kidney. Expressed at very low levels in a number of tumor-derived cell lines.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD745Hu01 Recombinant Low Density Lipoprotein Receptor Related Protein 12 (LRP12) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Low Density Lipoprotein Receptor Related Protein 12 (LRP12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Low Density Lipoprotein Receptor Related Protein 12 (LRP12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Low Density Lipoprotein Receptor Related Protein 12 (LRP12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Low Density Lipoprotein Receptor Related Protein 12 (LRP12) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Low Density Lipoprotein Receptor Related Protein 12 (LRP12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Low Density Lipoprotein Receptor Related Protein 12 (LRP12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Low Density Lipoprotein Receptor Related Protein 12 (LRP12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Low Density Lipoprotein Receptor Related Protein 12 (LRP12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Low Density Lipoprotein Receptor Related Protein 12 (LRP12) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Low Density Lipoprotein Receptor Related Protein 12 (LRP12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Low Density Lipoprotein Receptor Related Protein 12 (LRP12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Low Density Lipoprotein Receptor Related Protein 12 (LRP12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Low Density Lipoprotein Receptor Related Protein 12 (LRP12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Low Density Lipoprotein Receptor Related Protein 12 (LRP12) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of a novel gene encoding a putative transmembrane protein with altered expression in some human transformed and tumor-derived cell lines."Oncogene 18:335-342(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways."Biochemistry 42:7270-7282(2003) [PubMed] [Europe PMC] [Abstract]