Phosphatidic Acid Phosphatase Type 2C (PPAP2C)
[Edit]PPAP2-C; LPP2; PAP-2c; PAP2-g; Lipid phosphate phosphohydrolase 2; Phosphatidate phosphohydrolase type 2c
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Lipid phosphate phosphohydrolase 2 is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D.
This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site.
Phosphatidic Acid Phosphatase Type 2C has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPD698Hu01 | Recombinant Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | n/a | Monoclonal Antibody to Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Phosphatidic Acid Phosphatase Type 2C (PPAP2C) | ELISA Kit Customized Service Offer |
- "Molecular cloning of two alternatively spliced forms of human phosphatidic acid phosphatase cDNAs that are differentially expressed in normal and tumor cells."DNA Cell Biol. 17:377-385(1998) [PubMed] [Europe PMC] [Abstract]
- "Human type 2 phosphatidic acid phosphohydrolases. Substrate specificity of the type 2a, 2b, and 2c enzymes and cell surface activity of the 2a isoform."J. Biol. Chem. 273:22059-22067(1998) [PubMed] [Europe PMC] [Abstract]
- "Identification of a novel human phosphatidic acid phosphatase type 2 isoform."FEBS Lett. 427:188-192(1998) [PubMed] [Europe PMC] [Abstract]
- "The DNA sequence and biology of human chromosome 19." Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]