Acetyl Coenzyme A Acyltransferase 2 (ACAA2)
[Edit]DSAEC; T1; Mitochondrial 3-Oxoacyl-Coenzyme A Thiolase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase
Mammalian tissues have 5 known types of thiolase: ACAT2, which is involved in cholesterol biosynthesis, peroxisomal ACAA1, which is involved in beta-oxidation, mitochondrial ACAT1, which appears to function in ketone body metabolism, mitochondrial ACAA2, which catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral, and mitochondrial trifunctional protein, which also catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. The deduced 397-amino acid ACAA2 protein contains a putative 16-amino acid N-terminal mitochondrial targeting signal. Human and rat ACAA2 share 86.6% amino acid sequence identity. Northern blot analysis found a 1.6-kb ACAA2 transcript in human liver, fibroblasts, and intercostal muscle; ACAA2 expression was barely detectable in spleen and kidney.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPD659Hu01 | Recombinant Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAD659Hu01 | Polyclonal Antibody to Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | WB; IHC; ICC; IP; FCM |
Assay Kits | n/a | CLIA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPD659Mu01 | Recombinant Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAD659Mu01 | Polyclonal Antibody to Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Acetyl Coenzyme A Acyltransferase 2 (ACAA2) | ELISA Kit Customized Service Offer |
- "Cloning and sequence analysis of a full length cDNA encoding human mitochondrial 3-oxoacyl-CoA thiolase."Biochim. Biophys. Acta 1216:304-306(1993) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes."Biochem. J. 383:237-248(2004) [PubMed] [Europe PMC] [Abstract]
- "Acetyl-Coenzyme A acyltransferase 2 attenuates the apoptotic effects of BNIP3 in two human cell lines."Biochim. Biophys. Acta 1780:873-880(2008) [PubMed] [Europe PMC] [Abstract]
- "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]