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ATP Binding Cassette Transporter B10 (ABCB10)

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ABC-B10; M-ABC2; MTABC2; ATP-Binding Cassette Transporter 10; ABC Transporter 10 Protein; Mitochondrial ATP-Binding Cassette 2

ATP Binding Cassette Transporter B10 (ABCB10)
CCC D640
HGNC 41
MGI 1860508
PubMed 22884976
RGD 1311222
UniProt Q9NRK6
ABCB10 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown.
Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD640Hu01 Recombinant ATP Binding Cassette Transporter B10 (ABCB10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD640Hu01 Polyclonal Antibody to ATP Binding Cassette Transporter B10 (ABCB10) WB; IHC
Assay Kits n/a CLIA Kit for ATP Binding Cassette Transporter B10 (ABCB10) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATP Binding Cassette Transporter B10 (ABCB10) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD640Mu01 Recombinant ATP Binding Cassette Transporter B10 (ABCB10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD640Mu01 Polyclonal Antibody to ATP Binding Cassette Transporter B10 (ABCB10) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for ATP Binding Cassette Transporter B10 (ABCB10) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATP Binding Cassette Transporter B10 (ABCB10) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant ATP Binding Cassette Transporter B10 (ABCB10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to ATP Binding Cassette Transporter B10 (ABCB10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to ATP Binding Cassette Transporter B10 (ABCB10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for ATP Binding Cassette Transporter B10 (ABCB10) CLIA Kit Customized Service Offer
n/a ELISA Kit for ATP Binding Cassette Transporter B10 (ABCB10) ELISA Kit Customized Service Offer
  1. "M-ABC2, a new human mitochondrial ATP-binding cassette membrane protein."FEBS Lett. 478:89-94(2000) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Characterization and mapping of three new mammalian ATP-binding transporter genes from an EST database."Mamm. Genome 6:114-117(1995) [PubMed] [Europe PMC] [Abstract]
  5. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  8. "Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states."Proc. Natl. Acad. Sci. U.S.A. 110:9710-9715(2013) [PubMed] [Europe PMC] [Abstract]
  9. "Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population."J. Hum. Genet. 47:38-50(2002) [PubMed] [Europe PMC] [Abstract]
  10. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]