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Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3)

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PTPH1; Protein-tyrosine phosphatase H1

Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3)
CCC D586
HGNC 9655
MGI 105307
PubMed 16619586
RGD 1311363
UniProt P26045
Wiki PTPN3
Tyrosine-protein phosphatase non-receptor type 3 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta.Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD586Hu01 Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD586Hu01 Polyclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD586Mu01 Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD586Mu01 Polyclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) ELISA Kit Customized Service Offer
  1. "Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin."Proc. Natl. Acad. Sci. U.S.A. 88:5949-5953(1991) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "cDNA cloning of new protein tyrosine phosphatases in the human colon."Tumor Biol. 13:180-186(1992) [PubMed] [Europe PMC] [Abstract]
  6. "Expression of cytoskeletal-associated protein tyrosine phosphatase PTPH1 mRNA in human hepatocellular carcinoma."J. Gastroenterol. 29:727-732(1994) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  9. "Large-scale structural analysis of the classical human protein tyrosine phosphatome."Cell 136:352-363(2009) [PubMed] [Europe PMC] [Abstract]