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Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2)

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GCK; BL44; RAB8IP; B lymphocyte serine/threonine-protein kinase; Germinal center kinase; MAPK/ERK kinase kinase kinase 2; Rab8-interacting protein

Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2)
CCC D552
HGNC 6864
MGI 1346883
PubMed 8643544
RGD 1308199
UniProt Q12851
Wiki MAP4K2
Mitogen-activated protein kinase kinase kinase kinase 2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases.
This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.Highly expressed in germinal center but not mantle zone B-cells. Also expressed in lung, brain and placenta and at lower levels in other tissues examined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Mitogen Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2) ELISA Kit Customized Service Offer
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