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Myosin XVIIIA (MYO18A)

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MYSPDZ; MAJN; Molecule associated with JAK3 N-terminus; Myosin containing a PDZ domain

Myosin XVIIIA (MYO18A)
CCC D458
HGNC 31104
MGI 2667185
PubMed 19923322
UniProt Q92614
Wiki MYO18A
Myo18a-alpha contains a KE-rich region, an N-terminal PDZ domain, and a characteristic myosin homology region of head, neck (with 1 IQ motif), and coiled-coil tail. The Myo18a-beta isoform lacks the KE-rich region and PDZ domain. Myo18A-alpha is present in most tissues, while Myo18A-beta is expressed specifically in hematopoietic tissues and cell lines. Myo18a-alpha and Myo18a-beta as 230- and 190-kD proteins, respectively.
Myo18a-alpha colocalizes with the ER-Golgi complex and with membrane ruffles and filopodia, while Myo18a-beta localizes diffusely to the cytoplasm. Myo18a-alpha is expressed in mature but not immature macrophages. MYO18A localizes to the surface of COS-1 cells, and that MYO18A expression in COS-1 cells mediates SPA binding.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myosin XVIIIA (MYO18A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myosin XVIIIA (MYO18A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myosin XVIIIA (MYO18A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myosin XVIIIA (MYO18A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myosin XVIIIA (MYO18A) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myosin XVIIIA (MYO18A) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myosin XVIIIA (MYO18A) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myosin XVIIIA (MYO18A) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myosin XVIIIA (MYO18A) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myosin XVIIIA (MYO18A) ELISA Kit Customized Service Offer
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