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Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6)

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ESMLC; LC17-GI; LC17-NM; LC17A; LC17B; MLC1SM; MLC3NM; MLC3SM; 17 kDa myosin light chain; Myosin light chain alkali 3

Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6)
CCC D426
HGNC 7587
MGI 109318
PubMed 24517254
RGD 1589019
UniProt P60660
Wiki MYL6
Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. MYL6 is a myosin alkali light chain that is expressed in smooth muscle and non-muscle tissues. Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene.
Both deduced proteins contain 151 amino acids and differ from other MLCs in that they lack highly basic amino aids in their N termini. MLC3NM has a calculated molecular mass of 16.9 kD, whereas MLC3SM has a calculated molecular mass of 17 kD. Expression of MYL6 was highest in fibroblasts and myoblasts, lower in fetal muscle, and lowest in adult muscle.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD426Hu01 Recombinant Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD426Hu01 Polyclonal Antibody to Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) CLIA Kit Customized Service Offer
n/a ELISA Kit for Myosin Light Chain 6, Alkali, Smooth Muscle And Non Muscle (MYL6) ELISA Kit Customized Service Offer
  1. "The alkali light chains of human smooth and nonmuscle myosins are encoded by a single gene. Tissue-specific expression by alternative splicing pathways."J. Biol. Chem. 264:9009-9015(1989) [PubMed] [Europe PMC] [Abstract]
  2. "Characterization of human myosin light chains 1sa and 3nm: implications for isoform evolution and function."Mol. Cell. Biol. 10:1095-1104(1990) [PubMed] [Europe PMC] [Abstract]
  3. "Molecular cloning, sequencing, and characterization of smooth muscle myosin alkali light chain from human eye cDNA: homology with myocardial fatty acid ethyl ester synthase-III cDNA."Genomics 19:186-188(1994) [PubMed] [Europe PMC] [Abstract]
  4. "Molecular cloning and sequencing of myosin light chains in human megakaryoblastic leukemia cells."J. Smooth Muscle Res. 37:25-38(2001) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]