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Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9)

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SERPINA11b; GCET1; Centerin; Germinal center B-cell-expressed transcript 1 protein

Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9)
CCC D391
HGNC 15995
MGI 1919157
PubMed 24319541
RGD 1304789
UniProt Q86WD7
Wiki SERPINA9
SERPINA9 also known as centerin or GCET1 is a human gene. The protein encoded by this gene is a member of the serpin family of serine protease inhibitors.Highly expressed in normal germinal center (GC) B-cells and GC B-cell-derived malignancies.
The expression of SERPINA9 is restricted to germinal center B cells and lymphoid malignancies. SERPINA9 is likely to function in vivo in the germinal center as an efficient inhibitor of trypsin-like proteases. Protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro).

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) CLIA Kit Customized Service Offer
n/a ELISA Kit for Serpin Peptidase Inhibitor Clade A Member 9 (SERPINA9) ELISA Kit Customized Service Offer
  1. "Two newly characterized germinal center B-cell-associated genes, GCET1 and GCET2, have differential expression in normal and neoplastic B cells."Am. J. Pathol. 163:135-144(2003) [PubMed] [Europe PMC] [Abstract]
  2. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Molecular characterization of centerin, a germinal centre cell serpin."Biochem. J. 405:489-494(2007) [PubMed] [Europe PMC] [Abstract]
  7. "Expression of the serpin centerin defines a germinal center phenotype in B-cell lymphomas."Am. J. Clin. Pathol. 130:117-126(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Gcet1 (centerin), a highly restricted marker for a subset of germinal center-derived lymphomas."Blood 111:351-358(2008) [PubMed] [Europe PMC] [Abstract]