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Interleukin 17 Receptor E (IL17RE)

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IL17R-E

Interleukin 17 Receptor E (IL17RE)
CCC D348
HGNC 18439
MGI 1889371
PubMed 21993849
RGD 735148
UniProt Q8NFR9
Interleukin 17 Receptor E is a protein that shares limited similarity with the interleukin-17 receptor. The function of the encoded protein has not yet been determined. Three alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.
Functional IL-17R is a heteromeric complex consisting of at least IL17RA and IL17RC. A number of additional variants exist including IL17RB, which binds preferentially IL17B and IL17E.Receptor which can activate the MAPK signaling pathway and seems to function at or upstream of Ras By similarity. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Interleukin 17 Receptor E (IL17RE) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Interleukin 17 Receptor E (IL17RE) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Interleukin 17 Receptor E (IL17RE) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Interleukin 17 Receptor E (IL17RE) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 17 Receptor E (IL17RE) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD348Mu01 Recombinant Interleukin 17 Receptor E (IL17RE) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD348Mu01 Polyclonal Antibody to Interleukin 17 Receptor E (IL17RE) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 17 Receptor E (IL17RE) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 17 Receptor E (IL17RE) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD348Ra01 Recombinant Interleukin 17 Receptor E (IL17RE) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD348Ra01 Polyclonal Antibody to Interleukin 17 Receptor E (IL17RE) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 17 Receptor E (IL17RE) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 17 Receptor E (IL17RE) ELISA Kit Customized Service Offer
  1. "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Identification and functional characterization of a novel interleukin 17 receptor: a possible mitogenic activation through ras/mitogen-activated protein kinase signaling pathway."Cell. Signal. 18:1287-1298(2006) [PubMed] [Europe PMC] [Abstract]
  5. "IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens."Nat. Immunol. 12:1151-1158(2011) [PubMed] [Europe PMC] [Abstract]
  6. "IL-17C regulates the innate immune function of epithelial cells in an autocrine manner." Nat. Immunol. 12:1159-1166(2011) [PubMed] [Europe PMC] [Abstract]