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Proteasome Inhibitor Subunit 1 (PSMF1)

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PI31; Proteasome inhibitor PI31 subunit

Proteasome Inhibitor Subunit 1 (PSMF1)
CCC D324
HGNC 9571
MGI 1346072
PubMed 24770418
UniProt Q92530
Wiki PSMF1
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits.
Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Proteasome Inhibitor Subunit 1 (PSMF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Proteasome Inhibitor Subunit 1 (PSMF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proteasome Inhibitor Subunit 1 (PSMF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Proteasome Inhibitor Subunit 1 (PSMF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome Inhibitor Subunit 1 (PSMF1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Proteasome Inhibitor Subunit 1 (PSMF1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Proteasome Inhibitor Subunit 1 (PSMF1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Proteasome Inhibitor Subunit 1 (PSMF1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Proteasome Inhibitor Subunit 1 (PSMF1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Proteasome Inhibitor Subunit 1 (PSMF1) ELISA Kit Customized Service Offer
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  2. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  8. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  9. "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  11. "Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor."J. Biol. Chem. 283:22325-22335(2008) [PubMed] [Europe PMC] [Abstract]