Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1)
[Edit]COX4; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial
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COX is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. COX4I1 is the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPD286Hu01 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPD286Hu02 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
RPD286Hu03 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAD286Hu01 | Polyclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. |
MAD286Hu21 | Monoclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. | |
Assay Kits | SED286Hu | ELISA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SED286Mu | ELISA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPD286Ra01 | Recombinant Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAD286Ra01 | Polyclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. |
MAD286Ra21 | Monoclonal Antibody to Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | WB; IHC; ICC; IP. | |
Assay Kits | SED286Ra | ELISA Kit for Cytochrome C Oxidase Subunit IV Isoform 1 (COX4I1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
- "Isolation of a cDNA clone encoding subunit IV of human cytochrome c oxidase."Gene 55:205-217(1987) [PubMed] [Europe PMC] [Abstract]
- "Novel use of a chimpanzee pseudogene for chromosomal mapping of human cytochrome c oxidase subunit IV."Gene 86:209-216(1990) [PubMed] [Europe PMC] [Abstract]
- "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "The 5-prime region of the COX4 gene contains a novel overlapping gene, NOC4."Mamm. Genome 10:506-512(1999) [PubMed] [Europe PMC] [Abstract]
- "Subunit IV of human cytochrome c oxidase, polymorphism and a putative isoform."Biochim. Biophys. Acta 1119:218-224(1992) [PubMed] [Europe PMC] [Abstract]
- "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]