Ataxin 10 (ATXN10)

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E46L; SCA10; Spinocerebellar Ataxia 10; Brain protein E46 homolog

Ataxin 10 (ATXN10)
The presence of pyramidal and extrapyramidal symptoms and ophthalmoplegia makes the diagnosis of ADCA I, the presence of retinopathy points to ADCA II, and the absence of associated signs to ADCA III. Genetic linkage and molecular analyses revealed that ADCAs are genetically heterogeneous even within the various subtypes.
Ataxia 10 is a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of a pentanucleotide repeat in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD248Hu01 Recombinant Ataxin 10 (ATXN10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD248Hu01 Polyclonal Antibody to Ataxin 10 (ATXN10) WB; IHC; ICC; IP; FCM
MAD248Hu21 Monoclonal Antibody to Ataxin 10 (ATXN10) WB; IHC; ICC; IP.
Assay Kits SED248Hu ELISA Kit for Ataxin 10 (ATXN10) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD248Mu01 Recombinant Ataxin 10 (ATXN10) Positive Control; Immunogen; SDS-PAGE; WB.
RPD248Mu02 Recombinant Ataxin 10 (ATXN10) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD248Mu01 Polyclonal Antibody to Ataxin 10 (ATXN10) WB; IHC; ICC; IP.
PAD248Mu02 Polyclonal Antibody to Ataxin 10 (ATXN10) WB; IHC; ICC; IP.
Assay Kits SED248Mu ELISA Kit for Ataxin 10 (ATXN10) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ataxin 10 (ATXN10) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ataxin 10 (ATXN10) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ataxin 10 (ATXN10) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ataxin 10 (ATXN10) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ataxin 10 (ATXN10) ELISA Kit Customized Service Offer
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