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Sjogren Syndrome Antigen A2 (SSA2)

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RO60; TROVE2; RoRNP; TROVE Domain Family,Member 2; 60kDa Ribonucleoprotein Autoantigen SS-A/Ro; Autoantigen Ro, 60kDa; TROVE domain family member 2

Sjogren Syndrome Antigen A2 (SSA2)
CCC D197
HGNC 11313
MGI 106652
PubMed 7829096
RGD 1305083
UniProt P10155

The cDNA that encodes the 60-kD Ro/SSA autoantigen recognized by autoantibodies in certain lupus erythematosus and Sjogren syndrome sera was cloned and sequenced by Deutscher et al. and confirmed with minor differences by Ben-Chetrit et al..Ro autoantigens are of clinical significance because antibodies directed against them are found in most patients with primary Sjogren syndrome, subacute cutaneous lupus erythematosus, neonatal lupus erythematosus, ANA-negative lupus erythematosus, and systemic lupus erythematosus-like disease secondary to homozygous C2 or C4 complement deficiency. Ro antibody is a frequent cause of congenital heart block. Alspaugh and Tan described 3 types of precipitating antibodies in the serum of Sjogren patients; they designated the 3 types as SS-A, SS-B, and SS-C.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD197Hu01 Recombinant Sjogren Syndrome Antigen A2 (SSA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD197Hu01 Polyclonal Antibody to Sjogren Syndrome Antigen A2 (SSA2) WB; IHC; ICC; IP.
Assay Kits SED197Hu ELISA Kit for Sjogren Syndrome Antigen A2 (SSA2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD197Mu01 Recombinant Sjogren Syndrome Antigen A2 (SSA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD197Mu01 Polyclonal Antibody to Sjogren Syndrome Antigen A2 (SSA2) WB; IHC; ICC; IP.
Assay Kits SED197Mu ELISA Kit for Sjogren Syndrome Antigen A2 (SSA2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Sjogren Syndrome Antigen A2 (SSA2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Sjogren Syndrome Antigen A2 (SSA2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Sjogren Syndrome Antigen A2 (SSA2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Sjogren Syndrome Antigen A2 (SSA2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Sjogren Syndrome Antigen A2 (SSA2) ELISA Kit Customized Service Offer
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  6. , Submitted (FEB-2009) to UniProtKB
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